Paper
Synthesis and biological evaluation of 4-(substituted aryl)-1-(N-indolyl acetamidyl)-3-chloro-2-azetidinones
Published 2005 ยท P. Chowdary, S. G. Jawarkar, K. Rani
Indian Journal of Pharmaceutical Sciences
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Abstract
Various 4-(substituted aryl)-1-(N-indolyl acetamidyl)-3-chloro-2-azetidinones were prepared by condensing N-(arylidine hydrazidomethyl)-indoleswith chloroacetyl chloride. Their structures were established by chemical tests, IR and 1 HNMR spectral data. These synthesized compounds were tested for their antibacterial, antifungal, antitubercular and antiinflammatory activities.
4-(substituted aryl)-1-(N-indolyl acetamidyl)-3-chloro-2-azetidinones) show potential antibacterial, antifungal, antitubercular, and antiinflammatory activities.
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