Paper

Synthesis and evaluation of 6-[18F]fluoro-3-(pyridin-3-yl)-1H-indole as potential PET tracer for targeting tryptophan 2, 3-dioxygenase (TDO).

Published Dec 20, 2019 · Z. Qiao, K. Mardon, D. Stimson

Nuclear medicine and biology

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Abstract

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In Vitro Study

Study Snapshot

6-[18F]fluoro-3-(pyridine-3-yl)-1H-indole shows potential as a PET tracer for targeting tryptophan 2, 3-dioxygenase (TDO), with good affinity for the enzyme and no de-fluorination in vivo

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis and evaluation of 6-[18F]fluoro-3-(pyridin-3-yl)-1H-indole as potential PET tracer for targeting tryptophan 2, 3-dioxygenase (TDO).

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