Synthesis and evaluation of antitubercular activity of imidazo[2,1-b][1,3,4]thiadiazole derivatives.

doi:10.1016/J.BMC.2005.12.020

Paper

Synthesis and evaluation of antitubercular activity of imidazo[2,1-b][1,3,4]thiadiazole derivatives.

Published May 1, 2006 · G. Kolavi, V. Hegde, I. Khazi

Bioorganic & medicinal chemistry

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138

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1

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Abstract

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In Vitro Study

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Study Snapshot

Imidazo[2,1-b][1,3,4]thiadiazole derivatives show moderate antitubercular activity against Mycobacterium tuberculosis, with compounds 6a, 6b, 7c, and 8a showing the highest inhibitory activity.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis and evaluation of antitubercular activity of imidazo[2,1-b][1,3,4]thiadiazole derivatives.

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