Paper

Synthesis and biological evaluation of diverse tetrahydrobenzofuran-4-ones as potent antibacterial agents

Published Feb 25, 2015 · L. Xia, A. Idhayadhulla, Y. Lee

Journal of Industrial and Engineering Chemistry

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Abstract

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In Vitro Study

Study Snapshot

Tetrahydrobenzofuran-4-one derivatives show potent antibacterial activity against Gram-negative and Gram-positive bacteria, with compound 3b showing the highest activity against P. aeruginosa and S. aureus.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis and biological evaluation of diverse tetrahydrobenzofuran-4-ones as potent antibacterial agents

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