Synthesis and biological evaluation of new 2-chloro-3-((4-phenyl-1H-1,2,3-triazol-1-yl)methyl)quinoline derivatives via click chemistry approach.

doi:10.1016/j.ejmech.2010.04.002

Paper

Synthesis and biological evaluation of new 2-chloro-3-((4-phenyl-1H-1,2,3-triazol-1-yl)methyl)quinoline derivatives via click chemistry approach.

Published Jul 1, 2010 · Amol H. Kategaonkar, Pravin V. Shinde, Atul H. Kategaonkar

European journal of medicinal chemistry

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89

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Abstract

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In Vitro Study

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Study Snapshot

New 2-chloro-3-((4-phenyl-1H-1,2,3-triazol-1-yl)methyl)quinoline derivatives synthesized via click chemistry show significant antifungal and antibacterial activity against tested strains.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis and biological evaluation of new 2-chloro-3-((4-phenyl-1H-1,2,3-triazol-1-yl)methyl)quinoline derivatives via click chemistry approach.

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