Synthesis and pharmacological evaluation of novel 5-substituted-1-(phenylsulfonyl)-2-methylbenzimidazole derivatives as anti-inflammatory and analgesic agents.

doi:10.1016/j.ejmech.2010.01.067

Paper

Synthesis and pharmacological evaluation of novel 5-substituted-1-(phenylsulfonyl)-2-methylbenzimidazole derivatives as anti-inflammatory and analgesic agents.

Published Jun 1, 2010 · Monika Gaba, Dhandeep Singh, Sarbjot Singh

European journal of medicinal chemistry

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99

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Non-RCT

Animal Study

Highly Cited

Study Snapshot

Novel 5-substituted-1-(phenylsulfonyl)-2-methylbenzimidazole derivatives show moderate to good anti-inflammatory and analgesic activity with low ulcerogenicity compared to indomethacin.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis and pharmacological evaluation of novel 5-substituted-1-(phenylsulfonyl)-2-methylbenzimidazole derivatives as anti-inflammatory and analgesic agents.

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