Synthesis and biological evaluation of pyrrolo[2,3-b]pyridine analogues as antiproliferative agents and their interaction with calf thymus DNA.

doi:10.1016/j.ejmech.2016.02.059

Paper

Synthesis and biological evaluation of pyrrolo[2,3-b]pyridine analogues as antiproliferative agents and their interaction with calf thymus DNA.

Published May 23, 2016 · Suresh Narva, Surendar Chitti, Bhaskara Rao Bala

European journal of medicinal chemistry

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38

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1

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Abstract

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In Vitro Study

Study Snapshot

Novel pyrrolo[2,3-b]pyridine analogues show potential as anticancer agents by effectively inhibiting growth in various cancer cell lines and intercalating into calf thymus DNA.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis and biological evaluation of pyrrolo[2,3-b]pyridine analogues as antiproliferative agents and their interaction with calf thymus DNA.

References

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