Synthesis and antimicrobial evaluation of substituted (1,1'-biphenyl)-4-yl(3-methylbenzofuran-2-yl)methanones by Suzuki cross-coupling reaction

doi:10.1134/S1070363216120410

Paper

Synthesis and antimicrobial evaluation of substituted (1,1'-biphenyl)-4-yl(3-methylbenzofuran-2-yl)methanones by Suzuki cross-coupling reaction

Published Dec 1, 2016 · B. Reddy, V. P. Reddy

Russian Journal of General Chemistry

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Abstract

A series of new substituted [1,1'-biphenyl]-4-yl(3-methylbenzofuran-2-yl)methanones was prepared by Suzuki cross-coupling from (4-bromophenyl)(3-methylbenzofuran-2-yl)methanone. The obtained compounds were assayed for their in vitro antibacterial activity against different types of bacterial strains; antifungal activity was also examined by inhibitory effect against different fungal strains.

Study Snapshot

Substituted [1,1'-biphenyl]-4-yl(3-methylbenzofuran-2-yl)methanones show promising antibacterial and antifungal activity against various bacterial and fungal strains.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Paper

Synthesis and antimicrobial evaluation of substituted (1,1'-biphenyl)-4-yl(3-methylbenzofuran-2-yl)methanones by Suzuki cross-coupling reaction

References

Citations

Benzofuran derivatives and their anti-tubercular, anti-bacterial activities.

Benzofuran derivatives show potential as anti-tubercular and anti-bacterial agents, with excellent in vitro and vivo activities against both drug-sensitive and drug-resistant pathogens.