Synthesis and biological evaluation of new taxoids derived from 2-deacetoxytaxinine J.

doi:10.1016/J.BMCL.2006.12.101

Paper

Synthesis and biological evaluation of new taxoids derived from 2-deacetoxytaxinine J.

Published Mar 15, 2007 · M. Botta, S. Armaroli, D. Castagnolo

Bioorganic & medicinal chemistry letters

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86

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

In Vitro Study

Highly Cited

Study Snapshot

New taxoids derived from 2-deacetoxytaxinine J show potential as a new treatment for human mammary carcinoma MDR cells, with one showing activity at 0.1 microM when combined with paclitaxel.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis and biological evaluation of new taxoids derived from 2-deacetoxytaxinine J.

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