Paper

Synthesis of functionally diverse bicyclic sulfonamides as constrained proline analogues and application to the design of potential thrombin inhibitors

Published Aug 25, 2003 · S. Hanessian, Helen E. Sailes, Eric Therrien

Tetrahedron

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Abstract

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Study Snapshot

Bicyclic sulfonamides with different sizes of second rings were synthesized and evaluated for their potential as thrombin inhibitors.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis of functionally diverse bicyclic sulfonamides as constrained proline analogues and application to the design of potential thrombin inhibitors

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