2-bromo-1-(3,4-dimethylphenyl)ethanone (2) was prepared and converted to thiazole derivatives (6-11a-c, 14-20) through reactions with different reagents. Compounds (3, 5, 12, 13, 21) were prepared from reaction of compound (2) with 2-mercapto-4,6-dimethylnicotinonitrile1H-benzo[d]imidazole-2-thiol, p-chloroaniline, potassium cyanide and 2-aminobenzenethiol respectively. The synthesized compounds were confirmed by elemental analysis, IR, 1H-NMR and mass spectral analysis.

New thiazole derivatives synthesized from 2-bromo-1-(3,4-dimethylphenyl)ethanone show promising fungicidal activity against various fungi.

Paper

SYNTHESIS AND FUNGICIDAL ACTIVITY OF NEW THIAZOLE DERIVATIVES WERE PREPARED FROM 2-BROMO-1-(3,4-DIMETHYLPHENYL)ETHANONE

References

Citations