Synthesis of a hexahydropyrimido[1,2-a]azepine-2-carboxamide derivative useful as an HIV integrase inhibitor

doi:10.1016/J.TETLET.2007.09.072

Paper

Synthesis of a hexahydropyrimido[1,2-a]azepine-2-carboxamide derivative useful as an HIV integrase inhibitor

Published Nov 19, 2007 · M. Ferrara, B. Crescenzi, M. Donghi

Tetrahedron Letters

Q3 SJR score

12

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0

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Abstract

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Study Snapshot

The hexahydropyrimido[1,2-a]azepine-2-carboxamide derivative 1, which acts as an HIV integrase inhibitor, can be synthesized using three efficient strategies, allowing for multigram amounts of high purity and ee material.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Synthesis of a hexahydropyrimido[1,2-a]azepine-2-carboxamide derivative useful as an HIV integrase inhibitor

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