Paper
Direct synthesis of highly substituted thiophenes through copper(i)-catalyzed tandem reactions of alkylidenethiiranes with terminal alkynes.
Published Aug 21, 2009 · Yiping Zhang, M. Bian, W. Yao
Chemical communications
Q1 SJR score
17
Citations
1
Influential Citations
Abstract
A novel copper(i)-catalyzed tandem addition/cycloisomerization reaction of 1-phenylsulfonylalkylidenethiiranes with terminal alkynes for the convergent assembly of 2-(alpha-phenylsulfonylalkyl)-thiophenes is reported, which could directly assemble various functional groups incorporated into the thiophene ring.
Study Snapshot
Copper(i)-catalyzed tandem reactions of alkylidenethiiranes with terminal alkynes enable the direct synthesis of highly substituted thiophenes with various functional groups.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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