Paper
Synthesis, lipophilicity and antimicrobial properties of some O-(5-aryl-1,2,4-triazol-3-yl-ethyl)benzaldoximes and O-(5-aryl-1,3,4-oxydiazol-2-yl-ethyl)benzaldoximes.
Published May 1, 1998 · S. Papakonstantinou-Garoufalias, P. Marakos, A. Tsantili-Kakoulidou
Die Pharmazie
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7
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Abstract
The synthesis of benzaldehyde oximethers with suitably substituted 1,2,4-triazoles and 1,3,4-oxadiazoles from the corresponding benzaldoximes is described. The lipophilicity of the compounds was measured as well as their antimicrobial and antifungal activity in vitro. Certain compounds showed relatively significant activity against Bacillus subtilis.
In Vitro StudyStudy Snapshot
O-(5-aryl-1,2,4-triazol-3-yl-ethyl)benzaldoximes show significant antimicrobial activity against Bacillus subtilis, with some showing significant antifungal activity.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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