Synthesis of N-phenylsulfonamide derivatives and investigation of some esterase enzymes inhibiting properties.

doi:10.1016/j.bioorg.2020.104279

Paper

Synthesis of N-phenylsulfonamide derivatives and investigation of some esterase enzymes inhibiting properties.

Published Sep 17, 2020 · Elif Akin Kazancioglu, Murat Senturk

Bioorganic chemistry

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16

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Abstract

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In Vitro Study

Study Snapshot

N-phenylsulfonamide derivatives show potent inhibitory properties on carbonic anhydrase and cholinesterases, offering potential as new therapeutic drugs for diseases like edema, glaucoma, cancer, and osteoporosis.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis of N-phenylsulfonamide derivatives and investigation of some esterase enzymes inhibiting properties.

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