Synthesis and optimization of antitubercular activities in a series of 4-(aryloxy)phenyl cyclopropyl methanols.

doi:10.1016/j.ejmech.2010.09.063

Paper

Synthesis and optimization of antitubercular activities in a series of 4-(aryloxy)phenyl cyclopropyl methanols.

Published Dec 1, 2010 · S. S. Bisht, N. Dwivedi, V. Chaturvedi

European journal of medicinal chemistry

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10

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1

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Abstract

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In Vitro Study

Study Snapshot

Compound 36, a 4-(aryloxy)phenyl cyclopropyl methanol, shows 98% intracellular bacilli killing and is active against MDR, XDR, and rifampicin resistant strains of Mycobacterium tuberculosis H37R

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis and optimization of antitubercular activities in a series of 4-(aryloxy)phenyl cyclopropyl methanols.

References

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