Synthesis of oxadiazole-morpholine derivatives and manifestation of the repressed CD31 Microvessel Density (MVD) as tumoral angiogenic parameters in Dalton's Lymphoma.

doi:10.1016/j.bioorg.2015.04.008

Paper

Synthesis of oxadiazole-morpholine derivatives and manifestation of the repressed CD31 Microvessel Density (MVD) as tumoral angiogenic parameters in Dalton's Lymphoma.

Published Jun 1, 2015 · M. Al‐Ghorbani, V. Vigneshwaran, V. L. Ranganatha

Bioorganic chemistry

Q1 SJR score

30

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1

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Abstract

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In Vitro Study

Study Snapshot

Compound 6a, an oxadiazole-morpholine derivative, effectively reduces Dalton's Lymphoma tumor volume by 85% by inhibiting tumor vasculature.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis of oxadiazole-morpholine derivatives and manifestation of the repressed CD31 Microvessel Density (MVD) as tumoral angiogenic parameters in Dalton's Lymphoma.

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