Paper
The synthesis of o- and p-[18F]fluorobenzyl bromides and their application to the prepatation of labeled neuroleptics
Published Apr 1, 1991 · K. Hatano, T. Ido, R. Iwata
Journal of Labelled Compounds and Radiopharmaceuticals
Q3 SJR score
20
Citations
0
Influential Citations
Abstract
The syntheses of o- and p- [18F]fluorobenzyl bromides as labeled synthons were described. They were obtained from nitrobenzaldehyde via a three step synthesis that exhibited good yield. The preparation of [18F]fluororinated analog of a benzamide neuroleptic, cis-N-[(2RS, 3RS)-1-[18F]fluorobenzyl-2-methylpyrrolidin-3-yl] -5-chloro-2-methoxy-4-methylaminobenzamide, via N-benzylation with the synthons was also mentioned.
Study Snapshot
O- and p-[18F]fluorobenzyl bromides can be synthesized from nitrobenzaldehyde and used to prepare labeled neuroleptics.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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