Synthesis, electronic properties, antioxidant and antibacterial activity of some new benzimidazoles.

doi:10.1016/j.bmc.2015.08.029

Paper

Synthesis, electronic properties, antioxidant and antibacterial activity of some new benzimidazoles.

Published Oct 1, 2015 · A. Mavrova, D. Yancheva, N. Anastassova

Bioorganic & medicinal chemistry

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68

Citations

2

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Abstract

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In Vitro Study

Study Snapshot

New benzimidazole derivatives show high antioxidant and antibacterial activity, with 1,3-Diphenylpropyl-5-methyl-1,3-dihydro-2 H-benzimidazol-2-imine 14 showing significant activity against Bacillus subtilis, Staphylococcus au

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Synthesis, electronic properties, antioxidant and antibacterial activity of some new benzimidazoles.

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References

Citations

Synthesis of novel quinoline-thiazolobenzimidazolone hybrids as anticancer agents through caspase-dependent apoptosis.

Novel quinoline-thiazolobenzimidazolone hybrids show promising anticancer properties by activating caspase-dependent apoptosis, making them promising drug candidates.

A green and metal-free one-pot three-component synthesis of thiazolobenzimidazoles in sustainable deep eutectic solvent

Our environmentally friendly one-pot method for thiazolobenzimidazole derivatives enables up to 90% yield in 40 minutes, eliminating the need for bases, catalysts, and hazardous organic solvents.

Increased Absorption and Inhibitory Activity against Candida spp. of Imidazole Derivatives in Synergistic Association with a Surface Active Agent

Imidazole derivatives show improved antifungal activity when combined with sodium dodecyl sulphate, resulting in a synergistic effect against Candida spp.

Computational and experimental analysis of catalyst-free and expeditious synthesis of Benzo[4,5]imidazo[2,1-b]thiazole derivatives

This study presents a greener, catalyst-free approach for efficient synthesis of benzo[4,5]imidazo[2,1-b]thiazoles in less reaction time with sufficient purity, showing potential for diverse biologically active compounds.

Toxicological profiling of a de novo synthesized benzimidazole derivative with potent and selective proapoptotic potentials against breast cancer.

BMPE shows potent and selective proapoptotic potential against breast cancer cells, with tolerable toxicity and minimal-to-moderate histopathological alterations.

Employing nano-SnFe_2O_4 in the synthesis of arylbenzimidazoles, the computational study of the reaction mechanism, and examining the products as putative human transmembrane protein activators

Nano-SnFe_2O_4 catalysts efficiently synthesize arylbenzimidazoles, which show potential as activators of human innate immune system transmembrane proteins.

Biomedical applications of selective metal complexes of indole, benzimidazole, benzothiazole and benzoxazole: A review (From 2015 to 2022)

Indole, benzoxazole, benzothiazole, and benzimidazole compounds and their metal complexes have significant medicinal applications, including anti-ulcerogenic, anti-cancer, and antihypertensive properties.

The Discovery of Novel Antimicrobial Agents through the Application of Isocyanide-Based Multicomponent Reactions

Isocyanide-based multicomponent reactions (IMCRs) effectively discover novel antimicrobial compounds, offering potential for combating antibiotic resistance in the future.