Paper
Synthesis and properties of N-(aminoalkyl)-4-acetyl-3,5-dimethylpyrrole-2-carboxamides hydrochlorides.
Published Jan 1, 1993 · K. Bielawski, J. Bołtryk, D. Bartulewicz
Annals of the Medical University, Bialystok, Poland = Roczniki Akademii Medycznej w Bialymstoku
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Abstract
A series of N-(aminoalkyl)-4-acetyl-3,5-dimethylpyrrole-2-carboxamides hydrochlorides have been prepared and evaluated as cytostatic agents. General procedures were developed for constructing aminoalkyl chains on the 4-acetylpyrrole-2-carboxylic acid nuclei, utilizing 2-pyridone. The results of the preliminary biological activity have been mentioned.
N-(aminoalkyl)-4-acetyl-3,5-dimethylpyrrole-2-carboxamides hydrochlorides show potential as cytostatic agents, with promising results in preliminary biological activity.
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