A novel synthesis of cis-1-[[6-chloro-3-[(2-chloro-3-thienyl)methoxy]-2,3-dihydrobenzo[b]thien-2-yl]methyl]1h-imidazole : A new class of azole antifungal agents

doi:10.1016/S0040-4020(01)81691-4

Paper

A novel synthesis of cis-1-[[6-chloro-3-[(2-chloro-3-thienyl)methoxy]-2,3-dihydrobenzo[b]thien-2-yl]methyl]1h-imidazole : A new class of azole antifungal agents

Published 1988 · F. RaneDinanath, R. Pike, M. Puar

Tetrahedron

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18

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0

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Abstract

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Study Snapshot

This study successfully synthesized a new class of azole antifungal agents, cis-1-[6-chloro-3-[(2-chloro-3-thienyl)methoxy]-2,3-dihydrobenzo[b]thien-2-yl]methyl

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

A novel synthesis of cis-1-[[6-chloro-3-[(2-chloro-3-thienyl)methoxy]-2,3-dihydrobenzo[b]thien-2-yl]methyl]1h-imidazole : A new class of azole antifungal agents

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References

Citations

Synthesis and oxidative transformations of 2-functionalized 2-trifluoromethyltetrahydrothiophenes

2-acetoxymethyl- and 2-hydroxymethyl-2-(trifluoromethyl)tetrahydrothiophenes are useful precursors for a variety of new small fluorinated molecules, with potential applications in organic synthesis and catalysis.

Thermal Reactions of Polyfluoro-ortho-chloroarenethiols with Tetrafluoroethylene

Polyfluoro-ortho-chloroarenethiols with tetrafluoroethylene produce heptafluoro-5-chloro-2,3-dihydrobenzo[b]thiophene, 6-trifluoromethylheptafluor

Farnesyltransferase inhibitors: a comprehensive review based on quantitative structural analysis.

FTIs show potential in treating various cancers and other diseases, with potential for further development in the treatment of Progeria, malaria, and Trypnosomatid.

Preparation and rearrangement study of novel thiophenium- and selenophenium-ylides

Novel thiophenium- and selenophenium-ylides show remarkable stability and hindered rotation around the S-C ylide bond, with their thermal stability depending on their structure.

Synthesis of bicyclic biaryls as glucose-6-phosphatase inhibitors.

Bicyclic biaryls 6a, c, j, m, c, d, h show significant glucose-6-phosphatase inhibitory activity.