The synthetic procedure of 2,6-dimethyl-4-(3-nitrophenyl)-5-methoxycarbonyl-1,4-dihydropyridine-3-carboxylic acid was modified under phase transfer catalysis.The effects of catalyst amount,reaction time and solvent on the yield were investigated.The target compound was obtained in a total yield of 81% when using methanol as solvent under 70 ℃ for 4 h.

The modified phase transfer catalysis method for 2,6-dimethyl-4-(3-nitrophenyl)-5-methoxycarbonyl-1,4-dihydropyridine-3-carboxylic acid yields 81% with methanol as solvent under 70°C for 4 hours.

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Synthesis of 2,6-Dimethyl-4-(3-nitrophenyl)-5-methoxycarbonyl-1,4-dihydropyridine-3-carboxylic acid

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