Efficient synthesis of a (S)-fluoxetine intermediate using carbonyl reductase coupled with glucose dehydrogenase.

doi:10.1016/j.biortech.2017.10.097

Paper

Efficient synthesis of a (S)-fluoxetine intermediate using carbonyl reductase coupled with glucose dehydrogenase.

Published Feb 1, 2018 · Yunping Tang, Guomei Zhang, Z. Wang

Bioresource technology

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19

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Abstract

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Study Snapshot

Carbonyl reductase from Novosphingobium aromaticivorans effectively converts 3-chloro-1-phenyl-1-propanone to (S)-CPPO, offering potential for green industrial production of (S)-CPPO.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Efficient synthesis of a (S)-fluoxetine intermediate using carbonyl reductase coupled with glucose dehydrogenase.

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