Paper
Synthesis, Spectroscopic, and Thermal Analyses of 2-Oxo-1,2-dihydroquinolin-8-yl 4-chlorobenzoate
Published Jun 19, 2023 · Diana Becerra, Hugo Rojas, J. Castillo
Molbank
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Abstract
The 2-oxo-1,2-dihydroquinolin-8-yl 4-chlorobenzoate was synthesized in good yield using a triethylamine-mediated O-acylation reaction between 8-hydroxyquinolin-2(1H)-one and 4-chlorobenzoyl chloride in acetonitrile at room temperature. This methodology is notable for its clean reaction profile and straightforward procedure. The 2-oxoquinoline derivative was characterized using spectroscopic, spectrometric, and thermal analyses, enabling a comprehensive understanding of its molecular structure and thermal properties.
The 2-oxo-1,2-dihydroquinolin-8-yl 4-chlorobenzoate synthesized using a triethylamine-mediated O-acylation reaction shows good yield and a comprehensive understanding of its molecular structure and thermal properties.
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