Synthesis, crystal structure determination and antiproliferative activity of novel 2-amino-4-aryl-4,10-dihydro[1,3,5]triazino[1,2-a]benzimidazoles

doi:10.1016/J.MOLSTRUC.2011.10.054

Paper

DOI: 10.1016/J.MOLSTRUC.2011.10.054

Synthesis, crystal structure determination and antiproliferative activity of novel 2-amino-4-aryl-4,10-dihydro[1,3,5]triazino[1,2-a]benzimidazoles

Published Jan 11, 2012 · M. Hranjec, G. Pavlović, G. Karminski-Zamola,

Journal of Molecular Structure

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Abstract

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Study Snapshot

Novel 2-amino-4-aryl-4,10-dihydro[1,3,5]triazino[1,2-a]benzimidazoles show moderate antiproliferative activity against human cancer cell lines, with compound 4m being the most active.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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