Synthesis and Structure Elucidation of N′-(4-Methoxybenzylidene)-5-methyl-1-phenyl-1H-1,2,3-triazole-4-carbohydrazide

doi:10.3390/M1034

Paper

Synthesis and Structure Elucidation of N′-(4-Methoxybenzylidene)-5-methyl-1-phenyl-1H-1,2,3-triazole-4-carbohydrazide

Published Dec 2, 2018 · M. Alotaibi, H. Mohamed, B. F. Abdel-Wahab

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Abstract

N′-(4-Methoxybenzylidene)-5-methyl-1-phenyl-1H-1,2,3-triazole-4-carbohydrazide (3) was synthesized in a yield of 88% from an acid-catalyzed reaction of 5-methyl-1-phenyl-1H-1,2,3- triazole-4-carbohydrazide and 4-methoxybenzaldehyde in ethanol under reflux for 2.5 h. The structure of 3 was confirmed by the data obtained from infrared, nuclear magnetic resonance, mass spectroscopy, single crystal X-ray diffraction, and microanalysis.

Study Snapshot

N′-(4-Methoxybenzylidene)-5-methyl-1-phenyl-1H-1,2,3-triazole-4-carbohydrazide (3) is a novel compound with potential applications in pharmaceuticals and nutraceuticals.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Synthesis and Structure Elucidation of N′-(4-Methoxybenzylidene)-5-methyl-1-phenyl-1H-1,2,3-triazole-4-carbohydrazide

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References

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Novel triazoles of 3-acetylbetulin and betulone as anticancer agents

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A Simple Process for the Synthesis of Novel Pyrazolyltriazole and Dihydropyrazolylthiazole Derivatives as Antimicrobial Agents

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Citations

Synthesis and Structure Determination of 1-(4-Methoxyphenyl)-5-methyl-N’-(2-oxoindolin-3-ylidene)-1H-1,2,3-triazole-4-carbohydrazide

This study demonstrates the successful synthesis and structural determination of 1-(4-methoxyphenyl)-5-methyl-N'-(2-oxoindolin-3-ylidene)-1H-1,2,3-triazole-4-carbohydrazide (3), a novel tri

Ultrasound Assisted Chromatography-Free Synthesis of Triazolo [1,2-a]Indazole-Triones in the Presence of 1,4-Diazabicyclo[2.2.2] Octanium Diacetate as an Environmentally Friendly Green Media

Ultrasound-assisted chromatography-free synthesis of triazolo[1,2-a]indazole-triones using 1,4-diazabicyclo[2.2.2] octanium diacetate offers a simple, efficient, and eco-friendly method for synthesis of