Synthesis of some thiopyrimidine and thiazolopyrimidines starting from 2,6-dibenzylidene-3-methylcyclohexanone and its antimicrobial activities

doi:10.1016/J.ARABJC.2010.09.019

Paper

Synthesis of some thiopyrimidine and thiazolopyrimidines starting from 2,6-dibenzylidene-3-methylcyclohexanone and its antimicrobial activities

Published Oct 1, 2012 · Usama W. Hawas, M. Al-Omar, A. Amr

Arabian Journal of Chemistry

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Abstract

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Study Snapshot

Novel thiopyrimidine and thiazolopyrimidine derivatives synthesized from 2,6-dibenzylidene-3-methylcyclohexanone show promising antimicrobial activities.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Synthesis of some thiopyrimidine and thiazolopyrimidines starting from 2,6-dibenzylidene-3-methylcyclohexanone and its antimicrobial activities

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References

Citations

Access to Seleno‐Functionalized Thiazolo[3,2‐a]Pyrimidinones and Pyrimido[2,1‐b][1,3]Thiazinones via Selenocyclization of 2‐Alkenylthiopyrimidinones and Their Fused Analogs

This study developed a novel selenocyclization strategy for 2alkenylthiopyrimidinones and their fused analogs, revealing the impact of substrate structure and reaction conditions on regioselectivity.

Synthesis and Biofunctional Evaluation of Novel Isoxazole, C-Nucleoside, and Thioxopyrimidine Derivatives

This study synthesized and analyzed various isoxazole, C-Nucleoside, and thioxopyrimidine derivatives, evaluating their antibacterial and antifungal activity.

Synthesis of bis(ylidene) cyclohexanones and their antifungal activity against selected plant pathogenic fungi

Bis(ylidene) cyclohexanones show promising antifungal activity against Botrytis cinerea, Rhizoctonia solani, and Hemileia vastatrix, offering potential for novel agrochemicals.

Discovery of Novel Benzo[4,5]thiazolo(oxazolo)[3,2-a]pyrimidinone Mesoionic Derivatives as Potential Antibacterial Agents and Mechanism Research.

Compound A23 shows promising antibacterial activity against Xanthomonas oryzae pv. Oryzicola and Xanthomonas oryzae pv. oryzae, improving rice defense and oxidative phosphorylation pathway expression.

Synthesis of thiazolylidenethiazoloquinazolinone hybrids from monocarbonyl curcumin analogues. Characterization, bio-evaluation and DFT study

Compound D11, synthesized from monocarbonyl curcumin analogues, shows superior antimicrobial and antioxidant properties, with a more powerful antioxidant activity than the other compounds.