Synthesis and in vitro anticancer screening of some novel 4-[2-amino-3-cyano-4-substituted-5,6,7,8-tetrahydroquinolin-1-(4H)-yl]benzenesulfonamides.

doi:10.1016/j.ejmech.2010.03.030

Paper

Synthesis and in vitro anticancer screening of some novel 4-[2-amino-3-cyano-4-substituted-5,6,7,8-tetrahydroquinolin-1-(4H)-yl]benzenesulfonamides.

Published Jul 1, 2010 · M. Al-Said, M. Ghorab, S. I. Al-Qasoumi

European journal of medicinal chemistry

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49

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Abstract

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In Vitro Study

Study Snapshot

Novel 4-(quinolin-1-yl)benzenesulfonamide derivatives show promising in vitro anticancer activity, potentially acting through the inhibition of carbonic anhydrase isozymes.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis and in vitro anticancer screening of some novel 4-[2-amino-3-cyano-4-substituted-5,6,7,8-tetrahydroquinolin-1-(4H)-yl]benzenesulfonamides.

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