Synthesis and in vitro study of nitro- and methoxy-2-phenylbenzofurans as human monoamine oxidase inhibitors.

doi:10.1016/j.bioorg.2020.104616

Paper

Synthesis and in vitro study of nitro- and methoxy-2-phenylbenzofurans as human monoamine oxidase inhibitors.

Published Jan 5, 2021 · G. Delogu, Amit Kumar, G. Gatto

Bioorganic chemistry

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11

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Abstract

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In Vitro Study

Study Snapshot

The number and position of methoxyl groups on the 2-phenyl ring significantly influence the inhibitory activity of nitro- and methoxy-2-phenylbenzofurans as human monoamine oxidase inhibitors.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis and in vitro study of nitro- and methoxy-2-phenylbenzofurans as human monoamine oxidase inhibitors.

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