The ylide(4-carboxybutyl)triphenylphosphonium bromide,which was widely used in the synthesis of stereo selectivity drug,was synthesized from triphenylphosphine and 5-bromovaleric acid in the solution of acetonitrile.The structure of the product was confirmed by IR and 1HNMR.

The synthesis of ylide(4-carboxybutyl)triphenylphosphonium bromide from triphenylphosphine and 5-bromovaleric acid in acetonitrile provides a promising method for stereo selectivity drug synthesis.

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Synthesis of ylide(4-carboxybutyl)triphenylphosphonium bromide

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