Tandem regio- and stereospecific cyclization of ethyl isonicotinate with cyanoacetylenic alcohols to provide novel polycondensed heterocyclic systems

doi:10.1016/J.TETLET.2011.12.035

Paper

Tandem regio- and stereospecific cyclization of ethyl isonicotinate with cyanoacetylenic alcohols to provide novel polycondensed heterocyclic systems

Published Feb 22, 2012 · B. Trofimov, A. Mal’kina, V. V. Nosyreva

Tetrahedron Letters

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Abstract

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Study Snapshot

Ethyl isonicotinate reacts with tertiary cyanoacetylenic alcohols under mild conditions to produce novel polycondensed heterocyclic systems with 30-68% yields and regio- and stereospecific cyclization.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Tandem regio- and stereospecific cyclization of ethyl isonicotinate with cyanoacetylenic alcohols to provide novel polycondensed heterocyclic systems

References

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