Paper

Target identification and mechanism of action in chemical biology and drug discovery.

Published Apr 1, 2013 · DOI · M. Schenone, V. Dancík, B. Wagner

Nature chemical biology

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Abstract

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Study Snapshot

Target identification and mechanism-of-action studies play crucial roles in small-molecule probe and drug discovery, with various approaches needed to fully characterize on-target and off-target effects and understand small-molecule action mechanisms.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Target identification and mechanism of action in chemical biology and drug discovery.

References

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