Tert-butyl esters of N-protected amino acids with tert-butyl fluorocarbonate (Boc-F)

doi:10.1016/S0040-4039(01)93371-4

Paper

Tert-butyl esters of N-protected amino acids with tert-butyl fluorocarbonate (Boc-F)

Published 1989 · A. Loffet, Nathalie Galéotti, P. Jouin

Tetrahedron Letters

Q3 SJR score

10

Citations

0

Influential Citations

Full textSemantic Scholar

Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Study Snapshot

Tert-butyl fluorocarbonate (Boc-F) efficiently synthesizes tert-butyl esters of N-protected amino acids under mild conditions at room temperature in the presence of triethylamine and 4-dimethylamino-pyridine.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Sign up to use Study Snapshot

Consensus is limited without an account. Create an account or sign in to get more searches and use the Study Snapshot.

Create an account

Paper

Tert-butyl esters of N-protected amino acids with tert-butyl fluorocarbonate (Boc-F)

Sign up to use Study Snapshot

References

Citations

Solventless mechanosynthesis of N-protected amino esters.

Mechanochemical derivatization of N-protected amino acids in a ball mill leads to improved yields and simplified work-up procedures, reducing reaction times and simplifying work-up procedures.

Preparation of N-tBoc L-glutathione dimethyl and di-tert-butyl esters: versatile synthetic building blocks.

N-tBoc L-glutathione dimethyl and di-tert-butyl esters are versatile synthetic building blocks for the preparation of S-glutathione adducts.

Polypeptide Synthesis, Solid‐Phase Method

Solid-phase peptide synthesis (SPPS) has evolved since its inception in 1959, with current strategies covering protecting group combinations, coupling chemistry, monitoring, solid supports, cleavage, and purification.

Mild regeneration of the carboxylic group of amino acid alkyl esters by aqueous methanolic sodium hydrogen carbonate via 5-oxazolidinones

This study demonstrates a simple racemization-free procedure for regenerating the carboxylic acid group of amino acid alkyl esters using 5-oxazolidinones and sodium hydrogen carbonate in aqueous methanol.

Screening and identification of a novel lipase from Burkholderia sp. YY62 which hydrolyzes t-butyl esters effectively.

The novel lipase from Burkholderia sp. YY62 is 100-fold superior to commercial lipases in hydrolyzing t-butyl esters, making it a potential biofuel source.

Facile synthesis of tert-butyl ester of N-protected amino acids with tert-butyl bromide

This study presents a facile method for synthesizing various amino acid-tert-butyl ester derivatives under mild conditions, enabling the preparation of difficult-to-prepare amino Z-acid-Tert-butyl esters in high yields.