Both cis- and trans-3a,9b-dimethyl derivatives of 7-methoxy-1,3,3a,4,5,9b-hexahydrobenz[e]inden-2-one have been synthesised stereospecifically from 6-methoxy-1-tetralone. The trans-compound is a possible intermediate for the synthesis of triterpenes of the lanostane–cycloartane group.

This study demonstrates the stereospecific conversion of 6-methoxy-1-tetralone into 7-methoxy-trans-3a,9b-dimethyl-1,3,3a,4,5,9b-hexahydrobenz[e]inden-2-one, a potential intermediate for the synthesis

Journal of The Chemical Society-perkin Transactions 1

Tetracyclic triterpene synthesis. Part 1. Stereospecific conversion of 6-methoxy-1-tetralone into 7-methoxy-trans-3a,9b-dimethyl-1,3,3a,4,5-9b-hexahydrobenz[e]inden-2-one

Paper

Tetracyclic triterpene synthesis. Part 1. Stereospecific conversion of 6-methoxy-1-tetralone into 7-methoxy-trans-3a,9b-dimethyl-1,3,3a,4,5-9b-hexahydrobenz[e]inden-2-one

References

Citations