Paper
The Amniotic Band Syndrome
Published Mar 1, 1973 · DOI · J. Chemke, G. Graff, N. Hurwitz
Obstetrics & Gynecology
21
Citations
1
Influential Citations
Abstract
Amniotic fibrous bands may attach to various parts of the fetus or newborn and cause a variety of congenital malformations. The incidence has been estimated at approximately 1:5000 to 1:10,000 pregnancies. A case is reported in which a young, healthy woman gave birth to a premature infant, with intrauterine amputation of the left arm, and mummification and atrophy of -the still adherent distal part of the affected limb. Intrauterine amputation of the right middle finger was also found. The fetal side of the placenta revealed fine fibrous threads and bands. Two main theories of the pathogenesis of amniotic bands have been proposed: 1) the amniotic bands are the result of developmental defects occurring at the time of the formation of the germ disk and the amniotic cavity (endogenic origin), and 2) these bands generate from early rupture of the amnion (exogenic origin). Careful examination of the placenta is essential for a precise definition of the pathogenesis.
Amniotic bands can cause congenital malformations in fetuses and newborns, with two main theories of origin: developmental defects and early rupture of the amnion.
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