Paper
The Problem of the " Dangerous Carrier " of Hemolytic Streptococci. I. Number of Hemolytic Streptococci expelled by Carriers with Positive and Negative Nose Cultures.
Published Jul 1, 1945 · M. Hamburger, Margaret Green, V. Hamburger
The Journal of Infectious Diseases
62
Citations
0
Influential Citations
Abstract
That all carriers** of hemolytic streptococci*** are not equally capable of transmitting infection to others has become increasingly clear during recent years. Leonard Colebrook recognized, in 1933,1 that there were probably "dangerous" carriers, as well as relatively harmless ones among the general population. Hare,2 too, was impressed by the fact that though the average throat carrier rate for Group A streptococci in the normal population was about 7%, the number of cases of hemolytic streptococcal infection was relatively low. Coburn3'4 also stressed this problem and has suggested that biological changes take place in certain strains of streptococci which render them "communicable", as contrasted with ordinary strains which are not readily "communicable". During the course of studies in the transmission of hemolytic streptococcal infections over the past 2 years,5,6,7 certai facts have emerged which suggested that the most important difference between one carrier and another may reside in the actual number of hemolytic streptococci the carrier is capable of expelling, rather than in a fundamental biological change produced in the microorganisms by the carrier's tissues. These facts are:
The most important difference between carriers of hemolytic streptococci is the number of streptococci they are capable of expelling, rather than a fundamental biological change in their tissues.
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