A direct process for the trifluoromethylthiolation of allylic and benzylic alcohols under mild conditions has been developed. A wide range of free alcohols underwent nucleophilic substitution in the presence of stable CuSCF3 and BF3 ⋅Et2O to give the corresponding products in good to excellent yields.

This method allows for the direct trifluoromethylthiolation of allylic and benzylic alcohols under mild conditions, resulting in good to excellent yields of corresponding products.

Paper

Direct trifluoromethylthiolation of alcohols under mild reaction conditions: conversion of R-OH into R-SCF3.

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