Paper
Updates on gene editing and its applications.
Published Feb 28, 2022 · H. Puchta, Jiming Jiang, Kan Wang
Plant physiology
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Abstract
Recent advancements in gene editing provide unprecedented tools for plant biology research and offer unlimited potential for improving existing crops and de novo domesticating new crops. This Focus Issue on Gene Editing and Its Applications presents the latest technological innovations in gene editing, addresses challenges in using the technology in both basic and applied plant biology research, and provides perspectives on future developments of the field. This Focus Issue consists of 9 UPDATES written in-depth by experts in a subfield of gene editing, 16 research papers that highlight either a recent technological breakthrough or an application of gene editing in solving a biological question and/or in improving a crop. In this editorial, we first summarize the progresses made in developing new gene editing reagents, delivering reagents into plant cells, analyzing editing events on large scales, and removing transgenes. We then discuss the recent developments in achieving various types of genetic modifications including point mutations, gene targeting (GT), chromosome engineering, and epigenetic modifications. Furthermore, we highlight studies that use CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-mediated gene editing in crop improvements and de novo domestication using the examples provided in this Focus Issue. Programmable
Gene editing advances offer potential for improving crops and de novo domesticating new crops, with potential applications in basic and applied plant biology research.
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