Utility of 4,6-dichloro-2-(methylthio)-5-nitropyrimidine. An efficient solid-phase synthesis of olomoucine

doi:10.1016/S0040-4039(02)01953-6

Paper

DOI: 10.1016/S0040-4039(02)01953-6

Utility of 4,6-dichloro-2-(methylthio)-5-nitropyrimidine. An efficient solid-phase synthesis of olomoucine

Published Nov 4, 2002 · L. Hammarström, D. B. Smith, F. Talamas

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Abstract

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Study Snapshot

4,6-Dichloro-2-(methylthio)-5-nitropyrimidine efficiently synthesized olomoucine in a nine-step process, offering potential for regiocontrolled solution and solid-phase synthesis of highly substituted purines.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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