Paper

In vitro/in vivo effects of ethane dimethanesulfonate on Leydig cells of adult rats.

Published Mar 1, 1991 · DOI · G. Klinefelter, J. Laskey, N. L. Roberts

Toxicology and applied pharmacology

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Abstract

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In Vitro Study

Study Snapshot

Ethane dimethanesulfonate (EDS) exposure in Leydig cells compromises testosterone biosynthesis between cyclic adenosine monophosphate activation of protein kinase and cholesterol side chain cleavage enzyme, without affecting cell viability.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

In vitro/in vivo effects of ethane dimethanesulfonate on Leydig cells of adult rats.

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