Paper
IN VIVO BLOOD COMPATIBILITY OF REGENERATED SILK FIBROIN
Published Nov 10, 1989 · H. Sakabe, Hiraku Ito, T. Miyamoto
Sen-i Gakkaishi
121
Citations
1
Influential Citations
Abstract
Blood compatibility of regenerated silk fibroin was ecamined by in vivo blood tests. In vivo tests were made by a method of peripheral vein indelling suture. The coating of sample fibroin on the polyester suture was made by casting either from aqueous or from formic acid solution. The fibroin-coated sutures from aqueous solution were treated with methanolic aqueous solution in order to denature the silk fibroin, and implanted into a jugular and femoral vein of a dog. The results of the test method employed in this work indicate that the regenerated silk fibroin is nonthrombogenic.
Non-RCT
Animal Study
Highly CitedRegenerated silk fibroin is nonthrombogenic, as demonstrated by in vivo blood tests.
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