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These studies suggest that the normal range for A1C is generally considered to be below 5.7%.
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A1C, also known as hemoglobin A1C, is a blood test that measures the average level of blood sugar (glucose) over the past two to three months. It is a crucial marker for diagnosing and managing diabetes, as well as assessing the risk of developing diabetes in the future .
For the general population, the normal range of A1C is typically between 4.0% and 5.6%. Individuals with A1C levels within this range are considered to have normal blood sugar levels and a low risk of diabetes .
A1C levels between 5.7% and 6.4% are considered indicative of prediabetes. This range suggests that an individual has higher-than-normal blood sugar levels but not high enough to be classified as diabetes. People within this range are at an increased risk of developing type 2 diabetes and cardiovascular diseases .
An A1C level of 6.5% or higher on two separate tests indicates diabetes. This threshold is used by the International Expert Committee and other health organizations to diagnose diabetes without the need for additional plasma glucose concentration tests .
Individuals with A1C levels below 5.0% have a very low annualized incidence of diabetes, typically around 0.1%.
A1C levels in the range of 5.0% to 5.5% are associated with a slightly increased risk of developing diabetes, with an incidence rate of less than 9% over five years.
Those with A1C levels between 5.5% and 6.0% have a moderately increased risk, with a 9% to 25% incidence of diabetes over five years.
A1C levels in the range of 6.0% to 6.5% are associated with a high risk of developing diabetes, with an incidence rate of 25% to 50% over five years.
While A1C is a valuable tool for diagnosing and monitoring diabetes, it has limitations. For instance, it may not be sufficiently sensitive for detecting early diabetic states or impaired glucose tolerance (IGT) in some individuals. Approximately one-third of subjects with early diabetes and IGT have A1C levels below 5.7%, which is below the threshold for indicating an increased risk of developing diabetes .
Understanding the normal range of A1C levels is essential for diagnosing and managing diabetes effectively. While A1C provides a useful measure of average blood sugar levels, it is important to consider its limitations and use it in conjunction with other diagnostic tests when necessary. Regular monitoring and early intervention can help manage and reduce the risk of diabetes and its associated complications.
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