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These studies suggest anterior cerebral artery strokes can cause impaired motor control, leg weakness, behavioral disorders, and frontal dysfunctions, with some cases involving alien hand syndrome and hemiparesis in the lower limb.
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Anterior cerebral artery (ACA) strokes are relatively rare, accounting for only 0.5-3% of all ischemic strokes . These strokes can present with a variety of symptoms depending on the specific areas of the brain affected. The ACA supplies blood to the medial portions of the frontal lobes and superior medial parietal lobes, which are involved in higher motor control, cognition, and behavior .
Motor dysfunction is the most common symptom of ACA strokes, often presenting as contralateral hemiparesis with a predominance in the lower limbs . This is due to the involvement of the supplementary motor area and the paracentral lobule, which are critical for motor control of the legs. In some cases, patients may also experience early-onset spasticity.
ACA strokes can lead to significant behavioral and cognitive changes. Hypobulia, characterized by a lack of motivation or apathy, is frequently observed and is associated with damage to the frontal pole, corpus callosum, and cingulate gyrus. Other behavioral symptoms include psychomotor slowing, confusional states, and speech disturbances such as decreased verbal fluency .
In some cases, ACA strokes can result in alien hand syndrome (AHS), where patients experience involuntary hand movements that they cannot control. This is particularly associated with lesions in the pre-supplementary motor area (pre-SMA). Other motor control disturbances include exaggerated grasping, motor perseverations, and mirror movements.
Urinary incontinence is another symptom that can occur with ACA strokes, although it is not tied to specific lesion locations. The grasp reflex, which is an involuntary grasping of objects, is related to corpus callosum involvement.
Speech and language impairments, such as transcortical motor aphasia, can occur, especially with left-sided ACA infarctions. These impairments are often accompanied by mutism and hemiparesis.
Diagnosing ACA strokes can be challenging due to the variability in clinical presentation. Imaging techniques such as MRI and CT scans are crucial for identifying the specific areas of infarction and understanding the extent of the damage . In some cases, bilateral ACA strokes can present with whole-body numbness and transient inability to speak or move, complicating the diagnosis.
The prognosis for ACA stroke patients varies. While some patients show significant improvement in motor function over time, others may continue to experience persistent motor control deficits and behavioral changes . Long-term outcomes are generally favorable, but distinctive symptoms related to proximal ACA occlusion can impact dwelling and job status.
ACA strokes, though rare, present a unique set of symptoms that can significantly impact motor control, behavior, and cognition. Understanding the specific clinical patterns and utilizing advanced imaging techniques are essential for accurate diagnosis and effective management of these strokes. Despite the challenges, many patients can achieve favorable long-term outcomes with appropriate treatment and rehabilitation.
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