Anemia symptoms eyes
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Anemia Symptoms in the Eyes
Ocular Manifestations of Anemia
Anemia, a condition characterized by a deficiency of red blood cells or hemoglobin, can manifest in various ways, including through ocular symptoms. These symptoms are often indicative of the severity and type of anemia.
Retinal Hemorrhages and Other Retinal Findings
In patients with idiopathic aplastic anemia (AA), ocular manifestations are relatively common. A study involving 719 Korean patients with AA found that 37% of those who underwent retinal evaluations exhibited retinal hemorrhages. These hemorrhages were unilateral in some cases but more frequently bilateral. Additionally, other retinal findings included central retinal vein occlusion-like pictures, optic disc edema, cotton-wool spots, and macular edema 1. A literature review of 200 AA cases corroborated these findings, reporting retinal hemorrhages in 56% of cases and other retinal issues such as subhyaloid or vitreous hemorrhage, peripheral retinal vasculopathy, and optic disc edema 1.
Yellowish Eyes and Pale Conjunctiva
Anemia can also cause visible changes in the eyes, such as yellowish discoloration and pale conjunctiva. These symptoms are due to the reduced oxygen-carrying capacity of the blood and the resultant hypoxia. Yellowish eyes are a common symptom of anemia, often accompanied by fatigue and a general feeling of malaise 2. The pale conjunctiva is another hallmark of anemia, easily observable and often used in non-invasive diagnostic methods. Techniques such as Principal Component Analysis (PCA) and K-Nearest Neighbor (K-NN) have been employed to detect anemia through the conjunctiva, achieving high accuracy rates 3.
Conclusion
Ocular symptoms of anemia, including retinal hemorrhages, yellowish eyes, and pale conjunctiva, are significant indicators of the condition's presence and severity. These manifestations necessitate a multidisciplinary approach for effective management, involving hematologists and ophthalmologists. Early detection through both invasive and non-invasive methods can aid in timely intervention and better patient outcomes.
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Most relevant research papers on this topic
Ocular manifestations of idiopathic aplastic anemia: retrospective study and literature review
Aplastic anemia patients may experience ocular manifestations, such as retinal hemorrhage, optic disc edema, and dry eyes, requiring multidisciplinary management.
Anemia Detection Through Conjunctiva on Eyes Using Principal Component Analysis Method and K-Nearest Neighbor
Anemia detection through the conjunctiva of the eye using Principal Component Analysis and K-Nearest Neighbor methods has an accuracy of 87.5%, making it a non-invasive method for detecting anemia.
Peripapillary and macular vessel occlusions in sickle cell anemia.
Sickle cell anemia can cause peripheral retinal vessel occlusions and macular vessel occlusions, affecting vision in affected individuals.
Case ReportA Noninvasive Computerized Technique to Detect Anemia Using Images of Eye Conjunctiva
This study developed a noninvasive technique using eye conjunctiva images, achieving an accuracy of 93% in detecting anemia without invasive blood tests.
Prevalence and outcomes of anemia in geriatrics: a systematic review of the literature.
Anemia prevalence in elderly men ranges from 2.9% to 61%, with higher rates in men and women, and anemia increases with age, but current research on its impact on physical and cognitive function is limited.
Systematic Review
Highly CitedSymptomatology of anemia.
Raising hemoglobin levels with epoetin alfa significantly improves quality of life and functional status in cancer patients, potentially improving treatment efficacy and overall survival.
Highly CitedDetection of anemia from image of the anterior conjunctiva of the eye by image processing and thresholding
Our automated, non-invasive method for detecting anemia using an eye color analysis from a smartphone camera has a 78.9% accuracy, making it a viable alternative to invasive blood tests in underdeveloped areas.
Observational StudyAssociation Between Severity of Anemia in Patient with Chronic Kidney Failure to Retinal Hemorrhage
Severity of anemia in chronic kidney failure patients is not associated with retinal hemorrhage, and age does not influence retinal hemorrhage risk.
Observational Study