Searched over 200M research papers
10 papers analyzed
These studies suggest that a stroke can lead to death, with ischemic and hemorrhagic strokes being significant contributors to mortality.
8 papers analyzed
20 papers analyzed
Strokes are a significant global health concern, being the second-leading cause of death worldwide . In 2019 alone, strokes accounted for approximately 6.55 million deaths globally, representing 11.6% of total deaths. The mortality rates from stroke vary significantly depending on the type of stroke and the region. For instance, the 28-day mortality rate for ischemic stroke is around 3%, while it is much higher for intracerebral hemorrhage at 47% and subarachnoid hemorrhage at 19%.
The burden of stroke-related deaths is disproportionately higher in low- and middle-income countries (LMICs). These regions account for 87% of stroke-related deaths and 89% of disability-adjusted life years (DALYs) lost due to stroke . The age-standardized stroke-related mortality rate is significantly higher in low-income countries compared to high-income countries, being 3.6 times higher. This disparity is attributed to several factors, including limited access to healthcare, inadequate stroke management facilities, and higher prevalence of risk factors such as hypertension and diabetes.
The primary causes of death in stroke patients are often related to central nervous system complications, such as central respiratory and circulatory failure and brain herniation. Other significant causes include multiple organ failure, community-acquired lung infections, and hospital-acquired pneumonia. Sudden death, defined as death occurring within 24 hours of symptom onset, is also a notable outcome, accounting for 10-20% of all sudden deaths . This is often due to primary intracerebral or subarachnoid hemorrhage, with hypertension being a common underlying condition.
The risk of death remains high even after the initial stroke event. Within five years of a first stroke, the mortality rate is approximately 17%, with higher rates observed in cases of intracerebral hemorrhage (28%) compared to ischemic stroke (16%). Recurrent strokes are also a significant concern, with 41% of stroke survivors experiencing another stroke within five years.
In summary, strokes are a leading cause of death globally, with significant regional disparities in mortality rates. The primary causes of death in stroke patients are related to central nervous system complications and other systemic failures. Despite improvements in stroke management, the risk of death remains high, particularly in low- and middle-income countries. Effective prevention and timely intervention are crucial to reducing stroke-related mortality.
Most relevant research papers on this topic