Can lexapro make you tired

Pro Research Analysisby

Searched over 200M research papers

Analyzed relevant papers

Can Lexapro Make You Tired?

Lexapro and Fatigue

Lexapro, a commonly prescribed selective serotonin reuptake inhibitor (SSRI), is known to have several side effects, one of which is fatigue. Clinical trials have shown that fatigue is a notable adverse event among patients taking Lexapro. In placebo-controlled trials for Generalized Anxiety Disorder (GAD), fatigue was reported in 8% of patients treated with Lexapro, compared to only 2% in the placebo group . This indicates that fatigue is a relatively common side effect of Lexapro.

Lexapro and Somnolence

In addition to fatigue, somnolence, or drowsiness, is another side effect associated with Lexapro. The incidence of somnolence in patients taking Lexapro was found to be 13%, compared to 7% in those taking a placebo . This suggests that Lexapro can significantly increase the likelihood of experiencing drowsiness.

Dose Dependency of Fatigue and Somnolence

The occurrence of fatigue and somnolence appears to be dose-dependent. In patients with Major Depressive Disorder (MDD) receiving 20 mg/day of Lexapro, the incidence of somnolence was 9%, compared to 4% in those receiving 10 mg/day and 1% in the placebo group. Similarly, fatigue was reported in 6% of patients taking 20 mg/day, compared to 2% in both the 10 mg/day and placebo groups . This indicates that higher doses of Lexapro are more likely to cause fatigue and somnolence.

Conclusion

In summary, Lexapro can indeed make you tired. Both fatigue and somnolence are common side effects, with their incidence increasing at higher doses. If you are experiencing significant tiredness while taking Lexapro, it is advisable to consult your healthcare provider for potential adjustments to your treatment plan.

Sources and full results

Most relevant research papers on this topic

Dual-Source CT: Less Radiation, More Resolution

Lexapro may cause nausea, ejaculation disorder, insomnia, fatigue, decreased libido, and anorgasmia, but these events are less common than those in placebo-treated patients.

RCTLarge Human Trial

2008·

0citations

·B. Dixon

Serotonin syndrome in a patient taking Lexapro and Flexeril: a case report.

Serotonin syndrome can occur when Lexapro and Flexeril are combined, and cyclobenzaprine should be considered a potential precipitant.

Case Report

2008·

15citations

·Luke T. Day et al.

News in Brief

Lexapro is an effective and well-tolerated SSRI for treating major depressive disorder, offering quick relief with few side effects and low drug interactions.

RCT

2002·

0citations

SSRI withdrawal.

Stopping Lexapro gradually with a prescribing provider can minimize withdrawal symptoms and help ensure a safe transition.

1996·

1citation

·T. R. Mareth et al.

Escitalopram for the management of major depressive disorder: a review of its efficacy, safety, and patient acceptability

Escitalopram is an effective and well-tolerated treatment for major depressive disorder, with high patient acceptability and high continuity in antidepressant drug therapy.

Systematic ReviewRigorous JournalHighly Cited

2012·

71citations

·E. Kirino

Fast-scan cyclic voltammetry analysis of dynamic serotonin reponses to acute escitalopram.

Dynamic serotonin responses to SSRIs like escitalopram in mice may contribute to increased depression or suicidality after treatment onset.

Non-RCTAnimal Study

2013·

57citations

·K. Wood et al.

The efficacy of escitalopram in major depressive disorder: a multicenter randomized, placebo-controlled double-blind study

Both generic escitalopram and Lexapro effectively treat major depressive disorder, with both showing potent efficacy in reducing depression and anxiety levels.

RCTLarge Human Trial

2021·

3citations

·Xiaoliang Wang et al.

Creating a mouse academic research commons

PatientsLikeMe may be able to detect drug or treatment problems that have not shown up in clinical trials, potentially improving patient care.

2009·

10citations

·D. Einhorn et al.

Renal failure in a depressed adolescent on escitalopram.

Escitalopram, an SSRI, may cause acute renal failure in adolescents with major depressive disorder, highlighting the need for caution in its use in this population.

Case Report

2008·

3citations

·Kalpana Miriyala et al.

Efficacy and safety of generic escitalopram versus Lexapro in the treatment of major depression: a multicenter double-blinded randomized controlled trial

Generic escitalopram is as effective and safe as Lexapro in treating moderate to severe major depression in China, with careful monitoring of suicidal events.

RCTVery Rigorous Journal

2013·

4citations

·Yi-min Yu et al.

Try another search

does space end

drug disposal

best meds for sinus infection

antibiotics for sinus infection

110 by 70 blood pressure

black hole nearest