Can metoprolol cause sweating
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Can Metoprolol Cause Sweating?
Introduction to Metoprolol and Its Uses
Metoprolol is a beta-blocker commonly prescribed to manage hypertension, angina, and other cardiovascular conditions. It works by blocking beta-adrenergic receptors, which helps to reduce heart rate and blood pressure. However, like all medications, metoprolol can have side effects, one of which is sweating.
Sweating as a Side Effect of Metoprolol
Clinical Observations in Humans
Several studies have documented sweating as a side effect of metoprolol. In a crossover comparison study involving patients with mild hypertension, five patients reported experiencing sweating among other symptoms such as general malaise, palpitations, headache, and tremor during the first few days following abrupt withdrawal of metoprolol . This suggests that sweating can occur not only during active treatment but also during withdrawal from the medication.
Exercise-Induced Sweating
Another study examined the physiological responses to prolonged, submaximal exercise in hypertensive men treated with metoprolol. The researchers found that sweating from the forehead during exercise was enhanced by a single dose of metoprolol. This effect was maintained even after chronic treatment, indicating that metoprolol can increase sweating during physical activity .
Sweating in Response to Hypoglycemia
In a study investigating the effects of metoprolol on insulin-induced hypoglycemia, it was found that sweating was enhanced and prolonged by metoprolol. This suggests that metoprolol can exacerbate sweating in response to hypoglycemic events, which is particularly relevant for diabetic patients .
Sweating in Animal Studies
Interestingly, a study on the pharmacokinetics and cardiovascular effects of metoprolol in horses also reported sweating as the most common side effect. Although this study was conducted on animals, it provides additional evidence that metoprolol can cause sweating across different species .
Conclusion
In summary, multiple studies have shown that metoprolol can cause sweating as a side effect. This has been observed in various contexts, including during exercise, in response to hypoglycemia, and even in animal studies. Patients taking metoprolol should be aware of this potential side effect and consult their healthcare provider if they experience excessive sweating.
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