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These studies suggest that stroke can lead to death.
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Stroke is a significant global health issue, consistently ranked as one of the leading causes of death worldwide. According to the World Stroke Organization, stroke is the second-leading cause of death globally and the third-leading cause of death and disability combined, as measured by disability-adjusted life years (DALYs). This high mortality rate is echoed in various studies, which highlight the substantial and growing burden of stroke-related deaths .
The global burden of stroke has been increasing over the past few decades. From 1990 to 2019, the number of deaths from stroke increased by 43%. This trend is particularly pronounced in low- and middle-income countries, where the majority of stroke-related deaths occur . In these regions, stroke incidence has more than doubled over the last four decades, and stroke occurs on average 15 years earlier compared to high-income countries.
The risk of death following a stroke is significant both in the short term and long term. A study focusing on Chinese adults found that 28-day mortality rates were 3% for ischemic stroke, 47% for intracerebral hemorrhage, and 19% for subarachnoid hemorrhage. Long-term data from the same study indicated that mortality at five years post-stroke was 17% for ischemic stroke and 28% for intracerebral hemorrhage. These statistics underscore the severe and often fatal nature of stroke.
The primary causes of death in stroke patients are often related to central nervous system complications, such as central respiratory and circulatory failure and brain herniation. Other significant factors include multiple organ failure, community-acquired lung infections, and hospital-acquired pneumonia. Additionally, sudden death can occur due to disturbances in central autonomic control, leading to cardiac arrhythmias and myocardial injury.
In summary, stroke is a major cause of death globally, with a particularly high impact in low- and middle-income countries. The risk of death is significant both immediately following a stroke and in the long term. Understanding the causes and risk factors associated with stroke mortality is crucial for developing effective prevention and treatment strategies to reduce the global burden of this devastating condition.
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