choline chloride DES for herb extraction

Introduction

Choline chloride-based deep eutectic solvents (DES) have emerged as promising green solvents for the extraction of bioactive compounds from various plant materials. These solvents are considered environmentally friendly alternatives to traditional organic solvents due to their low toxicity, biodegradability, and high extraction efficiency.

Key Insights

High Extraction Efficiency of Phenolic Compounds:
- Choline chloride-based DESs have shown significantly higher extraction efficiency for phenolic compounds from rosemary, olive leaves, and Chinese wild rice compared to traditional solvents .
Optimization of Extraction Conditions:
- Optimal extraction conditions, such as temperature, water content, and solid-liquid ratio, have been identified to maximize the yield of bioactive compounds. For instance, optimal conditions for rosemary included 65°C, a liquid-solid ratio of 40:1, and 50% water content. Similarly, for Chinese wild rice, the optimal conditions were 51.2°C and a solid-liquid ratio of 37.0 mg/mL.
Antioxidant and Antimicrobial Activities:
- Extracts obtained using choline chloride-based DESs demonstrated significant antioxidant and antimicrobial activities, making them suitable for applications in food and pharmaceutical industries .
Biocompatibility and Biodegradability:
- Choline chloride-based DESs are characterized by low toxicity and high biodegradability, making them environmentally friendly alternatives to conventional solvents.
Versatility in Hydrogen Bond Donors:
- Various hydrogen bond donors (HBDs) such as 1,2-propanediol, ethylene glycol, and xylitol have been used in combination with choline chloride to tailor the DES properties for specific extraction needs .
Comparison with Traditional Solvents:
- Choline chloride-based DESs have been shown to outperform traditional solvents like ethanol and methanol in terms of extraction yield and efficiency for phenolic compounds from olive leaves and Ephedrae Herba .

Conclusion

Choline chloride-based deep eutectic solvents are highly effective for the extraction of bioactive compounds from various plant materials. They offer significant advantages over traditional solvents, including higher extraction efficiency, better antioxidant and antimicrobial properties, and greater environmental compatibility. The versatility in the choice of hydrogen bond donors allows for customization of DESs to optimize extraction processes for different bioactive compounds.

Choline chloride DES for herb extraction

Summary

Introduction

Key Insights

Conclusion

Sources and full results

Extraction of phenolic compounds from rosemary using choline chloride – based Deep Eutectic Solvents

Choline chloride-based deep eutectic solvents (DES) effectively extract rosemary leaves' phenolic compounds, resulting in good antioxidant and antimicrobial properties.

Biocompatible Deep Eutectic Solvents Based on Choline Chloride: Characterization and Application to the Extraction of Rutin from Sophora japonica

Choline chloride-based deep eutectic solvents are excellent, low-toxicity, biodegradable solvents for extracting rutin from Sophora japonica flower buds.

Choline chloride-based deep eutectic solvents as potential solvent for extraction of phenolic compounds from olive leaves: Extraction optimization and solvent characterization.

Choline chloride-based deep eutectic solvents (DES) extract 15% more phenolic compounds from olive leaves than ethanol, making them an innovative and strong solvent for phenolic compound extraction.

Optimizing Ultrasound-Assisted Deep Eutectic Solvent Extraction of Bioactive Compounds from Chinese Wild Rice

Choline chloride/1,4-butanediol (DES-2) is an efficient green solvent for extracting bioactive compounds from Chinese wild rice, offering greater extraction capacity than organic solvents.

Choline chloride-based deep eutectic solvents as green extractant for the efficient extraction of 1-butanol or 2-butanol from azeotropic n-heptane + butanol mixtures

Choline chloride-based deep eutectic solvents show potential as green extractants for efficient extraction of 1-butanol or 2-butanol from n-heptane + butanol mixtures, with potential for industrial applications.

Choline chloride derivative-based deep eutectic liquids as novel green alternative solvents for extraction of phenolic compounds from olive leaf

Choline chloride-ethyleneglycol deep eutectic solvents show potential as a sustainable alternative to traditional solvents for extracting phenolic compounds from olive leaf, with extraction yields similar to conventional solvents.

Evaluating the behaviour and principle of Deep Eutectic Solvent on Ephedrine-type alkaloids extraction from Ephedrae Herba.

Deep eutectic solvent (DES) composed of choline chloride and xylitol is an efficient and green solvent for extracting bioactive alkaloids from Ephedrae Herba, resulting in higher extraction yields than traditional solvents.

Choline Chloride Based Deep Eutectic Solvents as Promising Extractants of Flavonoids from Sedative Plant Composition

Choline chloride-based deep eutectic solvents show promising extraction efficiency for flavonoids from sedative plant compositions, surpassing traditional 70% ethanol extractants.

Choline chloride based deep eutectic solvents as extraction media for separation of n-hexane–ethanol mixture

Choline chloride-based deep eutectic solvents (DES) are more efficient than conventional ionic liquids for separating n-hexane-ethanol mixtures, with water being the most successful component.

Evaluation of toxicity and biodegradability of choline chloride based deep eutectic solvents.

Choline chloride-based deep eutectic solvents are environmentally friendly, non-toxic, and readily biodegradable, making them suitable for use in green technologies.

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