Covid chills
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COVID-19 and Chills: A Comprehensive Overview
Prevalence of Chills in COVID-19 Patients
Chills are a notable symptom in COVID-19 patients, though their prevalence varies across different studies. A systematic review and meta-analysis of 17,142 adult COVID-19 patients found that 14.45% experienced chills alongside fever. Another study highlighted that chills were reported by 15% of COVID-19 patients, making it a relatively common symptom. Additionally, chills were frequently observed in hospitalized patients, with a significant correlation to other severe symptoms such as chest tightness and lung abnormalities.
Chills as a Predictor of Severe COVID-19
Chills have been identified as a significant predictor of disease progression in COVID-19 patients. A retrospective study involving 211 patients found that the presence of chills increased the odds of progressing to severe COVID-19 by 6.32 times. This suggests that chills, along with other symptoms like elevated body temperature and abnormal chest X-ray findings, can be critical indicators for clinicians to monitor closely.
Chills in Symptom Profiles and Vaccine Side Effects
Chills are also a part of the broader symptom profile of COVID-19. In a study analyzing symptom data from a convenience sample of U.S. patients, chills were commonly reported alongside other symptoms such as fever, myalgia, headache, and fatigue. Furthermore, chills were frequently reported as a side effect of the COVID-19 mRNA-1273 vaccine among healthcare workers, indicating that this symptom is not only associated with the disease but also with the immune response triggered by vaccination.
Correlation with Laboratory and Clinical Characteristics
Chills have been positively correlated with several laboratory markers and clinical characteristics in COVID-19 patients. Elevated C-reactive protein (CRP) levels, which indicate inflammation, were commonly found in patients experiencing chills. This correlation underscores the inflammatory nature of COVID-19 and the role of chills as a symptom reflecting the body's response to the infection.
Conclusion
Chills are a significant symptom in COVID-19, with a prevalence that varies across different patient populations. They serve as an important predictor of disease severity and are commonly reported alongside other symptoms and vaccine side effects. Understanding the prevalence and implications of chills in COVID-19 can aid in better clinical management and monitoring of patients, potentially improving outcomes in those at risk of severe disease progression.
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